The antidepressive drug amitriptyline blocking a neuronal sodium channel
Amitriptyline is used as an antidepressant and antimigraine drug. It blocks sodium channels on neuronal membrans. Sodium channels generate and propagate action potentials in neurons and muscle. Source: PDB entry 6AGF
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Keywords:
actionamitryptilinanalgesicantidepressantantidepressiveantimigrainebiochemistrycellchannelcomplexdepolarizationdepressiondrugelectrochemicalglycoproteingradientillnessionmembranementalmigrainemuscleneuronpainparalysispotentialproteinsodiumsubunitvoltagegated
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