Gastroesophageal Reflux Disease
Gastroesophageal reflux disease (GERD), caused when the lower esophageal sphincter (LES) does not close properly, and stomach contents leak back (reflux) into the esophagus. When refluxed stomach acid touches the lining of the esophagus, it causes a burning sensation (heartburn). GERD may lead to histopathological changes in the esophagus.
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